EFFICACY & SAFETY
QUALITY OF LIFE
Frequent nasal allergies demand better management and control1
Ongoing exposure to increased allergens in the environment is a key factor to a rise in chronic allergic rhinitis, an increase in the severity of nasal allergy symptoms, and corresponding deterioration in patients’ quality of life.2,3
Surveys show that:
Suffering from allergic rhinitis may go beyond symptoms
Feelings of Depression
Flonase® Allergy Relief can help reduce symptoms of allergic rhinitis that affect quality of life
- Patients also reported an improved sense of well-being and a superior impact on attendance and performance at work, school, home, and in daily leisure/recreational activities as compared with patients treated with placebo and an antihistamine.6
- Effective symptom control with Flonase® Allergy Relief can also help relieve the tiredness and irritability associated with nasal allergies.7,8
- Significant relief of ocular itching and tearing due to nasal allergies10
- Clinicians reported that Flonase® provided a >40% improvement of total ocular symptom scores (TOSS) in 7 days vs. 26% with placebo and a 50% improvement of TOSS in 14 days vs. 31% with placebo.†10
Treats nasal allergy symptoms
Proven effective for seasonal and perennial allergic symptoms
- In a study of seasonal allergic rhinitis (SAR) symptom relief, patients who took Flonase® experienced >2x the reduction of symptom scores at day 4, and sustained this outcome through the duration of the study‡13
- In 59% of patients with perennial allergic rhinitis (PAR), Flonase® significantly lowered total nasal symptoms scores (TNSS)—measuring the sum of obstruction, rhinorrhea, sneezing, and itching—at week one and throughout treatment§14
- In some patients, Flonase® Allergy Relief starts to act on allergy symptoms in the first day.9
- Maximum benefit could take 2-3 days after the start of therapy.9
For maximum benefit, advise patients with allergies to continue taking Flonase® Allergy Relief for 1 week, then make it part of their daily routine.§6,9 Ensure patients are taking Flonase® Allergy Relief properly.
If symptoms are under control after 1 week of use, the dose should be lowered to 1 spray in each nostril once a day. Adults 18 years of age and older who need to use daily for longer than 3 months, should consult a doctor.
A well-established safety profile6
Flonase® Allergy Relief is a corticosteroid with low (<1%) systemic absorption.6 Low-systemic absorption minimizes the potential for systemic side effects that are a concern with other corticosteroids used to treat allergic rhinitis, such as prednisone.15,16
Approved to treat year-round symptoms6
Flonase® Allergy Relief:
Is NOT associated with higher blood pressure and is not contraindicated in patients with:9
- Heart disease
- Liver disease
- Kidney disease
Is NOT associated with common side effects associated with some other allergy medications.
- Beggs PJ. Impacts of climate change on aeroallergens: past and future. Clin Exp Allergy. 2004;34(10):1507-1513.
- D’Amato G. Urban air pollution and plant-derived respiratory allergy. Clin Exp Allergy. 2000;30(5):628-636.
- Géhanno P, Desfougeres JL. Fluticasone propionate aqueous nasal spray compared with oral loratadine in patients with seasonal allergic rhinitis. Allergy. 1997;52(4):445-450.
- Brooks M. Allergic rhinitis a significant burden. http://www.medscape.com/viewarticle/739928. Published March 30, 2011. Accessed March 27, 2014.
- World Allergy Organization. World Allergy Organization (WAO) White Book on Allergy. Milwaukee, WI: World Allergy Organization; 2011.
- Data on file. GlaxoSmithKline. 2016.
- Craig TJ, Teets S, Lehman EB, Chinchilli VM, Zwillich C. Nasal congestion secondary to allergic rhinitis as a cause of sleep disturbance and daytime fatigue and the response to topical nasal corticosteroids. J Allergy Clin Immunol. 1998;101(5):633-637.
- Sardana N, Craig TJ. Congestion and sleep impairment in allergic rhinitis. Asian Pac J Allergy Immunol. 2011;29(4):297-306.
- Flonase® Allergy Relief Product Monograph. GlaxoSmithKline Consumer Healthcare Inc. August 23, 2016.
- Nasacort Allergy 24HR/Nasacort AQ Product Monograph. Sanofi-Aventis Canada Inc. December 11, 2013.
- WebMD. Can nasal steroids ease allergy symptoms? http://www.webmd.com/allergies/nasal-steroids. Accessed October 14, 2014.
- DeWester J, Philpot EE, Westlund RE, Cook CK, Rickard KA. The efficacy of intranasal fluticasone propionate in the relief of ocular symptoms associated with seasonal allergic rhinitis. Allergy Asthma Proc. 2003;24(5):331-337.
- Darnell R, Pecoud A, Richards DH. A double-blind comparison of fluticasone propionate aqueous nasal spray, terfenadine tablets and placebo in the treatment of patients with seasonal allergic rhinitis to grass pollen. Clin Exp Allergy. 1994;24(12):1144-1150.
- Benincasa C, Lloyd RS. Evaluation of fluticasone propionate aqueous nasal spray taken alone and in combination with cetirizine in the prophylactic treatment of seasonal allergic rhinitis. Drug Invest. 1994;8(4):225-233.
- Nathan RA, Bronsky EA, Fireman P, et al. Once daily fluticasone propionate aqueous nasal spray is an effective treatment for seasonal allergic rhinitis. Ann Allergy. 1991;67(3):332-338.
- Banov CH, Woehler TR, LaForce CF, et al. Once daily intranasal fluticasone propionate is effective for perennial allergic rhinitis. Ann Allergy. 1994;73(3)240-246.
- MedlinePlus. Prednisone. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a601102.html. Accessed April 1, 2014.
- Greiner AN, Meltzer EO. Overview of the treatment of allergic rhinitis and nonallergic rhinopathy. Proc Am Thorac Soc. 2011;8(1):121-131.
- MedlinePlus. Clemastine. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682542.html. Accessed April 1, 2014.
- MedlinePlus. Diphenhydramine. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682539.html. Accessed April 1, 2014.
- MedlinePlus. Chlorpheniramine. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682543.html. Accessed April 1, 2014.
- MedlinePlus. Pseudoephedrine. http://www.nlm.nih.gov/medlinepous/druginfo/meds/a682619.html. Accessed April 1, 2014.